Fig. S5
- ID
- ZDB-FIG-150513-29
- Publication
- Ma et al., 2015 - Jag1b is essential for patterning inner ear sensory cristae by regulating anterior morphogenetic tissue separation and preventing posterior cell death
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fgf10a is expressed in the sensory cristae. (A-C) Whole-mount in situ hybridization of fgf10a in jag1b+/+, jag1b+/-, and jag1b-/- embryos at 48 hpf stage. Probe: fgf10a anti-sense. fgf10a is expressed in the sensory cristae (arrow heads). In jag1b-/- embryos, the anterior and posterior cristae are lost. (D-E) Whole-mount in situ hybridization of fgf10a in jag1b+/+, jag1b+/-, and jag1b-/- embryos at 30 hpf stage. Probe: fgf10a anti-sense. In jag1b-/- embryos, fgf10a expression is not affected in the anterior prosensory domain. (G) Sensory cristae development is not affected by Akt inhibitor treatment. Lateral views with anterior to the left and dorsal up. |
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Stage Range: | Prim-15 to Long-pec |