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General Information
ZIRC
ZFIN ID: ZDB-FIG-150304-3
Philipp et al., 2014 - Overlapping and Opposing Functions of GRK2 and GRK5 during Heart Development. The Journal of biological chemistry   289(38):26119-30 Full text @ J. Biol. Chem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage: Long-pec
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Long-pec

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
myh6 WT control Long-pec atrium ISH
WT standard conditions Long-pec atrium ISH
WT + MO1-grk3 standard conditions Long-pec atrium ISH
WT + MO1-grk5 standard conditions Long-pec atrium ISH
myh7 WT control Long-pec cardiac ventricle ISH
WT standard conditions Long-pec cardiac ventricle ISH
WT + MO1-grk3 standard conditions Long-pec cardiac ventricle ISH
WT + MO1-grk5 standard conditions Long-pec cardiac ventricle ISH
myl7 WT control Long-pec heart ISH
WT standard conditions Long-pec heart ISH
WT + MO1-grk3 standard conditions Long-pec heart ISH
WT + MO1-grk5 standard conditions Long-pec heart ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-grk3 standard conditions Prim-5 heart contraction increased rate, abnormal
Prim-5 regulation of heart contraction disrupted, abnormal
Long-pec atrium dilated, abnormal
Long-pec cardiac ventricle decreased size, abnormal
Long-pec heart contraction decreased rate, abnormal
Long-pec pericardium edematous, abnormal
Long-pec regulation of heart contraction disrupted, abnormal
WT + MO1-grk5 standard conditions Prim-5 heart contraction decreased rate, abnormal
Long-pec heart decreased size, abnormal
Long-pec heart contraction decreased rate, abnormal
Long-pec pericardium edematous, abnormal
Long-pec regulation of heart contraction disrupted, abnormal
Full text @ J. Biol. Chem.