FIGURE

Fig. 5

ID

ZDB-FIG-141112-21

Publication

Park et al., 2014 - A Single Mutation in the Acetylcholine Receptor ?-Subunit Causes Distinct Effects in Two Types of Neuromuscular Synapses

Other Figures

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Fig. 5

Nonfunctional AChRs in fast muscles of the love sofa mutant. A, Wild-type (left) and love sofa (right) larvae were doubly labeled with mAb35 antibody (green) and SV2 antibody (magenta). Boxes of dashed lines indicate myoseptal synapses in slow muscles. Arrowheads indicate distributed synapses in fast muscles. Scale bar, 50 μm. B, Representative traces of voltage-clamped slow and fast muscles in response to the application of 30 μM ACh. Calibration: 5 s, 500 pA. C, Amplitudes of ACh-induced currents in slow (n = 7) and fast muscles (n = 6) are shown. Each dot represents a muscle cell.

Expression Data

Antibodies:	Ab-SV2 Ab1-chrna
Fish:	AB/TU chrnd^nia06/nia06 (AB/TU)
Anatomical Terms:	fast muscle cell acetylcholine-gated channel complex fast muscle cell neuromuscular junction slow muscle cell acetylcholine-gated channel complex slow muscle cell neuromuscular junction
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	chrnd^nia06/nia06 (AB/TU)
Observed In:	fast muscle cell acetylcholine-gated channel complex fast muscle cell neuromuscular junction slow muscle cell acetylcholine-gated channel complex slow muscle cell neuromuscular junction
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Neurosci.