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Fig. 5 Nonfunctional AChRs in fast muscles of the love sofa mutant. A, Wild-type (left) and love sofa (right) larvae were doubly labeled with mAb35 antibody (green) and SV2 antibody (magenta). Boxes of dashed lines indicate myoseptal synapses in slow muscles. Arrowheads indicate distributed synapses in fast muscles. Scale bar, 50 μm. B, Representative traces of voltage-clamped slow and fast muscles in response to the application of 30 μM ACh. Calibration: 5 s, 500 pA. C, Amplitudes of ACh-induced currents in slow (n = 7) and fast muscles (n = 6) are shown. Each dot represents a muscle cell.
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Full text @ J. Neurosci.