FIGURE

Fig. 2

ID

ZDB-FIG-141007-103

Publication

Cardozo et al., 2014 - Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle

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Fig. 2

(a–j) In situ hybridization analysis for two optic stalk markers, pax2.1 (a–d) and fgf8a (f–i) at 28 hpf and 24 hpf, respectively. Embryos are shown in lateral (a,b,f,g) and frontal (c,d,h,i) views. Expression patterns of both genes are schematically represented in e and j. In cdon^ATG morphants, pax2.1 expression is expanded dorsally in the optic stalk (b,d brackets) when compared with controls (a,c brackets). Fgf8a expression is expanded caudally and laterally in the optic stalk (g,i arrowhead and dotted lines) as well as in the telencephalon (g,i) when compared with control embryos (f,h arrowhead and dotted lines). di, diencephalon; mes, mesencephalon; MHB, midbrain–hindbrain boundary; os, optic stalk; rh, rhombencephalon; tel, telencephalon. Scale bars, 100 μm.

Expression Data

Genes:	fgf8a pax2a
Fish:	WT WT + MO1-cdon
Knockdown Reagent:	MO1-cdon
Anatomical Terms:	diencephalon dorsal region hindbrain midbrain hindbrain boundary optic cup ventral region optic stalk telencephalon
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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