Morpholino
MO1-cdon
- ID
- ZDB-MRPHLNO-141021-1
- Name
- MO1-cdon
- Previous Names
-
- ATG (1)
- Target
- Sequence
-
5' - ATAATCTCAGGCCACCGTCCTCCAT - 3'
- Disclaimer
- Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
- Note
-
Translation-blocking MO.
- Genome Resources
- None
Target Location
Genomic Features
No data available
Expression
Gene expression in Wild Types + MO1-cdon
| Expressed Gene | Anatomy | Figures |
|---|---|---|
| fgf8a |
Fig. 2 
from Cardozo et al., 2014 |
|
| nkx2.1 |
Fig. S3
from Cardozo et al., 2014 |
|
| nkx2.2a |
Fig. S3
from Cardozo et al., 2014 |
|
| pax2a |
Fig. 2 ,
Fig. 3 ,
Fig. S3
from Cardozo et al., 2014 |
|
| pdzrn3b |
Fig. S3
from Cardozo et al., 2014 |
|
| rdh10a |
Fig. S3
from Cardozo et al., 2014 |
|
| tbx5a |
Fig. S3
from Cardozo et al., 2014 |
Phenotype
Phenotype resulting from MO1-cdon
| Phenotype | Fish | Figures |
|---|---|---|
| optic fissure closure incomplete, abnormal | WT + MO1-cdon |
Fig. S2
from Cardozo et al., 2014 |
Phenotype of all Fish created by or utilizing MO1-cdon
| Phenotype | Fish | Conditions | Figures |
|---|---|---|---|
| optic fissure closure incomplete, abnormal | WT + MO1-cdon | standard conditions |
Fig. S2
from Cardozo et al., 2014 |
Citations
- Deng, Z., Ran, Q., Chang, W., Li, C., Li, B., Huang, S., Huang, J., Zhang, K., Li, Y., Liu, X., Liang, Y., Guo, Z., Huang, S. (2024) Cdon is essential for organ left-right patterning by regulating dorsal forerunner cells clustering and Kupffer's vesicle morphogenesis. Frontiers in cell and developmental biology. 12:14297821429782
- Cardozo, M.J., Sánchez-Arrones, L., Sandonis, A., Sánchez-Camacho, C., Gestri, G., Wilson, S.W., Guerrero, I., Bovolenta, P. (2014) Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle. Nature communications. 5:4272
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