FIGURE
Fig. 3
- ID
- ZDB-FIG-140923-27
- Publication
- Lin et al., 2014 - Hypoxia-Inducible Factor 2 Alpha Is Essential for Hepatic Outgrowth and Functions via the Regulation of leg1 Transcription in the Zebrafish Embryo
- Other Figures
- All Figure Page
- Back to All Figure Page
Fig. 3
Hif2-alpha plays a major role in liver development. The specificity of knockdown by MO was demonstrated by monitoring lfabp gene expression at 5 pdf by WISH in wild-type embryos (A) and embryos injected with hif2-alpha ATG-MO (B). The small liver phenotype resulting from the knockdown of hif2-alpha can be rescued by co-injection of hif2-alpha mRNA (C). ATG-MO of hif2-alpha but not hif1-alpha caused the small liver phenotype (E). ATG-MO of hif3-alpha also caused a slight effect on liver development (F). |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Knockdown Reagents: | |
| Anatomical Term: | |
| Stage: | Day 5 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Day 5 |
Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ PLoS One