FIGURE

Fig. 2

ID

ZDB-FIG-140923-26

Publication

Lin et al., 2014 - Hypoxia-Inducible Factor 2 Alpha Is Essential for Hepatic Outgrowth and Functions via the Regulation of leg1 Transcription in the Zebrafish Embryo

Other Figures

All Figure Page

Back to All Figure Page

Fig. 2

Knockdown of hif2-alpha confers a small liver phenotype.

(A?J) Development of the embryonic liver was monitored by the expression pattern of the lfabp gene in wild-type embryos and hif2-alpha ATG-MO-injected embryos at 1?5 dpf by WISH, thereby revealing a small liver phenotype in hif2-alpha morphants. (K) Expression of the lfabp and fabp10a genes was investigated in wild-type embryos and hif2-alpha morphants at 5 dpf by qPCR (n = 30). Expression was normalized to β-actin. WT, wild type. The experiment was performed in triplicate, error bars indicate S.D. *, p<0.05, unpaired t-test.

Expression Data

Gene:	fabp1a
Fish:	WT WT + MO1-epas1b
Knockdown Reagent:	MO1-epas1b
Anatomical Term:	hepatocyte
Stage Range:	Prim-5 to Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-epas1b
Knockdown Reagent:	MO1-epas1b
Observed In:	liver
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One