FIGURE

Fig. 4

ID

ZDB-FIG-140902-127

Publication

Zennaro et al., 2014 - Podocyte developmental defects caused by adriamycin in zebrafish embryos and larvae: a novel model of glomerular damage

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Fig. 4

Clearance of 70-kDa dextran in 80 hpf larvae.

(a) a control larva immediately after dextran injection (0 hpi) shows distribution of fluorescence through the body, with major fluorescence in the heart and the eye. (b) representative images of untreated and treated fish at 24 hpi. Exposure to adriamycin causes dose-dependent loss of eye fluorescence, whereas the marker is retained in the cardiac area, due to pericardial edema. The graphs show quantification data of fluorescence intensity (obtained from 30 fish per condition and time point) in the pericardial area (c) and the eye (d). *** = P<0.0001 vs NT.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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