FIGURE

Fig. 4

ID

ZDB-FIG-140416-41

Publication

Viringipurampeer et al., 2014 - Rip3 knockdown rescues photoreceptor cell death in blind pde6c zebrafish

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Fig. 4

Expression patterns of caspase-independent cell death markers. (a–c) Wild-type (wt) retinal images. (d–f) Mutant pde6c^-/- (mt) retinal images. (a and d) Double labelling of calpain in green and zpr1 cone-specific marker in red. A few cells express calpain in the inner retina (white arrows). Scale bar=20μm. (b ande) Double labelling of parp in green and zpr1 in red. (c and f) rip1 co-labelling in red on GFP-expressing cone transgenic background. (g) Western blot of calpain (capn), parp and rip1 at 7d.p.f. Positive (+ve) controls: for parp and capn, mouse E14.5 eye tissue; for rip1, HEK293 cell line. Gapdh used to normalize gel loading

Expression Data

Gene:	EGFP
Antibody:	zpr-1
Fish:	WT pde6c^w59/w59 ucd1Tg pde6c^w59/w59; ucd1Tg
Anatomical Terms:	green sensitive photoreceptor cell red sensitive photoreceptor cell retinal cone cell
Stage:	Day 4

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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