FIGURE

Fig. 4

ID

ZDB-FIG-140313-38

Publication

Fekany et al., 1999 - The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures

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Fig. 4

TGF-β signaling suppresses the boz phenotype. (A,B) ntl expression (blue) normally marks notochord precursors (nt) and tail bud in wild-type embryos (A). In boz embryos, ntl expression in notochord precursors is absent (B) (5-7 somites). (C,D hgg1 expression (red) in the prospective hatching gland (hg) of a wild-type embryo (C) is reduced in boz^m168 mutants (D). (EG) Overexpression of TARAM-A-D (E), murine Nodal (F) and BMP-Vg1 (G) resulted in ectopic ntl and hgg1 expression domains in the majority of embryos from wild-type and boz^m168/m168 parents. (A,B) Dorsal view, (C,D) Frontal view; in all images anterior is to the top. Scale bar, 200 μm.

Expression Data

Genes:	ctslb tbxta
Fish:	WT dharma^m168/m168 (AB)
Anatomical Terms:	notochord polster tail bud
Stage:	5-9 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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