ZFIN ID: ZDB-FIG-140307-15
Kobayashi et al., 1998 - Overexpression of the forebrain-specific homeobox gene six3 induces rostral forebrain enlargement in zebrafish. Development (Cambridge, England)   125:2973-2982
Anatomical Terms:
Stage Range: Prim-5 to Long-pec

Fig. 4 six3 expression in later development. (A) Lateral view of 24- hour embryo showing six3 expression at the rostral surface of the forebrain (bracket); the eyes were removed. (B,C) Lateral (B) or frontal (C) view of six3 expression at 36 hours. The six3 signal (blue) is localized in the medial telencephalon (arrow), optic stalk (open triangle) and near the olfactory nerve (thin arrow). Axons were stained with antibody against acetylated α-tubulin (brown). (D,E) Lateral views of six3 (D) or lim3 (E) expression at 48 hours. six3 is expressed in the pituitary anlage (black triangle). Additional abbreviations: ac, anterior commissure; cb, cerebellum; dd, dorsal diencephalon; e, epiphysis; hy, hypothalamus; poc, postoptic commissure; rh, rhombomeres; t, telencephalon; te, tectum. Scale bars, 200 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
lhx3 WT standard conditions Long-pec adenohypophysis ISH
six3b WT standard conditions Prim-5 forebrain anterior surface ISH
Prim-5 hypothalamus ISH
Prim-5 tegmentum ISH
Prim-25 hypothalamus ISH
Prim-25 olfactory system ISH
Prim-25 tegmentum ISH
Prim-25 telencephalon medial region ISH
Long-pec adenohypophysis ISH
Long-pec hypothalamus ISH
Long-pec tegmentum ISH
Long-pec telencephalon ISH
Antibody Labeling Details No data available
Phenotype Details No data available
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