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General Information
ZIRC
ZFIN ID: ZDB-FIG-140224-29
Liang et al., 2012 - The stat3/socs3a Pathway Is a Key Regulator of Hair Cell Regeneration in Zebrafish stat3/socs3a Pathway: Regulator of Hair Cell Regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience   32(31):10662-10673 Full text @ J. Neurosci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibody:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-15 to Day 5
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-15 to Pec-fin

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
atoh1a WT standard conditions Pec-fin hair cell ISH
WT + MO3-socs3a standard conditions Pec-fin hair cell ISH
Pec-fin hindbrain ISH
Pec-fin otic vesicle ISH
Pec-fin spinal cord ISH
WT + MO4-socs3a standard conditions Pec-fin hair cell ISH
Pec-fin hindbrain ISH
Pec-fin otic vesicle ISH
Pec-fin spinal cord ISH
EGFP zf106Tg standard conditions Prim-15 otic vesicle IHC
zf106Tg + MO1-stat3 standard conditions Prim-15 otic vesicle IHC
socs3a WT standard conditions Day 5 anterior lateral line neuromast ISH
Day 5 posterior lateral line neuromast ISH
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-myo6 IHC zf106Tg standard conditions Prim-15 hair cell anterior macula
IHC Prim-15 hair cell posterior macula
IHC zf106Tg + MO1-stat3 standard conditions Prim-15 hair cell anterior macula
IHC Prim-15 hair cell posterior macula
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-stat3 standard conditions Long-pec otic vesicle has fewer parts of type otolith, abnormal
Pec-fin neuromast has fewer parts of type hair cell, abnormal
Pec-fin posterior lateral line neuromast decreased amount, abnormal
WT + MO3-socs3a standard conditions Pec-fin neuromast has fewer parts of type hair cell, abnormal
Pec-fin posterior lateral line neuromast decreased amount, abnormal
WT + MO4-socs3a standard conditions Pec-fin neuromast has fewer parts of type hair cell, abnormal
Pec-fin posterior lateral line neuromast decreased amount, abnormal
zf106Tg + MO1-stat3 standard conditions Prim-15 anterior macula has fewer parts of type hair cell anterior macula, abnormal
Full text @ J. Neurosci.