FIGURE

Fig. 6

ID

ZDB-FIG-131015-35

Publication

Zhang et al., 2013 - Tissue factor pathway inhibitor-2: A novel gene involved in zebrafish central nervous system development

Other Figures

(all 14)

All Figure Page

Back to All Figure Page

Fig. 6

Three members of the Notch pathway were downregulated. (A) The graph shows the results of qPCR analyses of her4, mib and Notch1α mRNA levels when ztfpi-2 was knocked down at 24 hpf. Asterisks indicate a significant difference from the Mcon-MO group (Student′s t test, P<0.05). (B) Results of qPCR showed that both her4 and mib were reduced as early as 3 somites stage. ((C), (D)) WISH indicated that her4 and mib were downregulated while ztfpi-2 mRNA could partially recover their expression at 3 somites stage and 25 hpf.

Expression Data

Genes:	her4.2 mib1 notch1a
Fish:	AB AB + MO1-tfpi2
Knockdown Reagent:	MO1-tfpi2
Anatomical Term:	whole organism
Stage Range:	Bud to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 381(1), Zhang, Y., Wang, L., Zhou, W., Wang, H., Zhang, J., Deng, S., Li, W., Li, H., Mao, Z., and Ma, D., Tissue factor pathway inhibitor-2: A novel gene involved in zebrafish central nervous system development, 38-49, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.