Gene

mib1

ID
ZDB-GENE-030404-2
Name
mindbomb E3 ubiquitin protein ligase 1
Symbol
mib1 Nomenclature History
Previous Names
  • mib
  • cg5841 (1)
  • chunp6889
  • fe47f05
  • im:7148100 (1)
  • KIAA1323 (1)
  • mind bomb
  • white tail (3)
  • wit (3)
  • wu:fe47f05 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Exhibits identical protein binding activity and ubiquitin-protein transferase activity. Involved in several processes, including animal organ development; nervous system development; and tube morphogenesis. Localizes to endocytic vesicle; perinuclear region of cytoplasm; and protein-containing complex. Is expressed in nervous system; neural tube; and pectoral fin. Used to study epilepsy. Human ortholog(s) of this gene implicated in left ventricular noncompaction. Orthologous to human MIB1 (mindbomb E3 ubiquitin protein ligase 1).
Genome Resources
Note
None
Expression
All Expression Data
11 figures from 9 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
126 figures from 74 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mib1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Left ventricular noncompaction 7 615092
Associated With mib1 Via Experimental Models
Human Disease Fish Conditions Citations
epilepsy mib1hi904Tg/hi904Tg standard conditions Hortopan et al., 2010
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000433 Zinc finger, ZZ-type
Domain IPR001841 Zinc finger, RING-type
Domain IPR010606 Mib-herc2
Domain IPR020683 Ankyrin repeat-containing domain
Domain IPR040847 Mind bomb, SH3 repeat domain
Domain IPR042056 E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Homologous_superfamily IPR037252 Mib/herc2 domain superfamily
Homologous_superfamily IPR043145 Zinc finger, ZZ-type superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain Ankyrin repeat-containing domain superfamily E3 ubiquitin-protein ligase MIB1/2, zinc finger, ZZ-type Mib-herc2 Mib/herc2 domain superfamily Mind bomb, SH3 repeat domain Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, ZZ-type Zinc finger, ZZ-type superfamily
UniProtKB:H9GYU5 1041
UniProtKB:A0A0R4IZE1 233
UniProtKB:B3DGQ0 1041
UniProtKB:A0A0R4IHW3 1038
UniProtKB:A0A140LFN2 237
UniProtKB:Q804S5 1030
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations