Gene

her4.2

ID
ZDB-GENE-060815-1
Name
hairy-related 4, tandem duplicate 2
Symbol
her4.2 Nomenclature History
Previous Names
  • Hes5d (1)
  • fe18g04 (1)
  • si:ch73-21g5.3 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in peripheral nervous system neuron axonogenesis. Predicted to localize to nucleus. Is expressed in several structures, including brain; eye; midbrain neural keel; neural plate; and neural tube. Orthologous to human HES5 (hes family bHLH transcription factor 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
15 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With her4.2 Human Ortholog
No data available
Associated With her4.2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003650 Orange domain
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR050370 Hairy and Enhancer of Split/HEY-related
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Hairy and Enhancer of Split/HEY-related Helix-loop-helix DNA-binding domain superfamily Myc-type, basic helix-loop-helix (bHLH) domain Orange domain
UniProtKB:B0V3D1 152
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA her4.2-202 (1) Ensembl 1,694 nt
mRNA her4.2-203 (1) Ensembl 1,737 nt
mRNA her4.2-204 (1) Ensembl 1,799 nt
mRNA her4.2-205 (1) Ensembl 1,804 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations