FIGURE
Fig. 4
- ID
- ZDB-FIG-130814-20
- Publication
- Ketley et al., 2013 - The miR-30 MicroRNA Family Targets smoothened to Regulate Hedgehog Signalling in Zebrafish Early Muscle Development
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Fig. 4
Analysis of Ptc1 reveals the position of miR-30 regulation in the Hh pathway. Ptc1 in situ hybridization shows the level of Hh pathway activity in different embryo treatment types. (A) Wild type embryo, (B) miR-30 overexpression embryo, (C) miR-30 morpholino injected embryo, (D) dnPKA overexpression embryo (E) dnPKA RNA injected with miR-30 duplex (F) Shh overexpression embryo (G) Reduced ptc1 expression is seen in Shh overexpression embryos coinjected with miR-30 RNA as miR-30 is able to suppress pathway activity. |
Expression Data
| Gene: | |
|---|---|
| Fish: | |
| Knockdown Reagent: | |
| Anatomical Term: | |
| Stage: | Prim-5 |
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Knockdown Reagent: | |
| Observed In: | |
| Stage: | Prim-5 |
Phenotype Detail
Acknowledgments
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