FIGURE

Fig. 4

ID

ZDB-FIG-130503-31

Publication

Lin et al., 2013 - The Critical Role of Protein Arginine Methyltransferase prmt8 in Zebrafish Embryonic and Neural Development Is Non-Redundant with Its Paralogue prmt1

Other Figures

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Fig. 4

Defective phenotypes at gastrulation and early segmentation stage of the zebrafish prmt8 morphants.

(A) Zebrafish embryos not injected (WT), injected with control AMO (standard) or 2 ng of prmt8 MO2 were stained with an endodermal marker sox 17 (animal pole views) or a mesodermal marker tbx6 (side views) at 6 hpf, and an ectodermal marker otx2 at 7 hpf. (B) Zebrafish embryos not injected, injected with control AMO or 2 ng of prmt8 MO2 were stained with myoD or ntl at 11 hpf (dorsal views).

Expression Data

Genes:	myod1 otx2b sox17 tbx6
Fish:	WT WT + MO2-prmt8b
Knockdown Reagent:	MO2-prmt8b
Anatomical Terms:	forerunner cell group presumptive mesoderm segmental plate
Stage Range:	Shield to Bud

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO2-prmt8b
Knockdown Reagent:	MO2-prmt8b
Observed In:	axial mesoderm structural organization notochord whole organism anterior-posterior axis
Stage:	Bud

Phenotype Detail

Acknowledgments

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