ZFIN ID: ZDB-FIG-130225-10
Dong et al., 2012 - Suppression of rap1 impairs cardiac myofibrils and conduction system in zebrafish. PLoS One   7(11):e50960 Full text @ PLoS One
Knockdown Reagents:
Observed In:
Stage: Protruding-mouth

Fig. S2

Morphant zebrafish has consistent defects in cardiac looping. Compared to control mp157e embryos (A, B), rap1MO injected mp157e embryos, crossed in flk1:mCherry background, showed faulty heart tube ā€˜Sā€™ loop and thin cavity, in both ventral and lateral views (C,D). Shown are ventral view (A, C) and lateral view (B, D), with anterior to the left.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
pku5Et; pku6Tg + MO1-rap1aa + MO2-rap1b + MO4-tp53 standard conditions Protruding-mouth heart looping disrupted, abnormal
Protruding-mouth heart morphology, abnormal
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One