FIGURE

Fig. S3

ID
ZDB-FIG-130222-10
Publication
Li et al., 2011 - Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation
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Fig. S3

Set8a acts synergistically with Wnt signaling in regulating zebrafish embryo development. (A) Set8a boosted the LEF1-luc in NIH 3T3. (B) In situ hybridization for expression of zebrafish set8a. set8a is broadly expressed at the 16-cell stage, sphere stage, and 60% epiboly. By 24 h postfertilization (hpf), set8a is more highly expressed in the brain region and blood island. Embryos hybridized with set8a sense probe were the negative control. (C) Injection of set8a mRNA rescued the set8a morphant phenotype. The morphants were classified into four categories: 0, S1, S2, and S3. (D) The set8a MO acted synergistically with the wnt8 MOs. The morphants were classified into four categories: 0, W1, W2, and W3.

Expression Data
Gene:
Fish:
Anatomical Terms:
Stage Range: 16-cell to Prim-5

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
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