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General Information
ZIRC
ZFIN ID: ZDB-FIG-120717-39
Kim et al., 2012 - Antagonistic Regulation of PAF1C and p-TEFb Is Required for Oligodendrocyte Differentiation. The Journal of neuroscience : the official journal of the Society for Neuroscience   32(24):8201-8207 Full text @ J. Neurosci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Long-pec to Day 4
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Day 4

Fig. 1 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
EGFP leo1knu6/knu6; vu12Tg standard conditions Long-pec motor neuron axon IFL
Day 4 Not Detected spinal cord oligodendrocyte IFL
vu12Tg standard conditions Long-pec motor neuron axon IFL
Day 4 spinal cord oligodendrocyte IFL
plp1a AB standard conditions Day 4 spinal cord oligodendrocyte ISH
AB + MO3-cdc73 standard conditions Day 4 Not Detected spinal cord oligodendrocyte ISH
leo1knu6/knu6 standard conditions Day 4 Not Detected spinal cord oligodendrocyte ISH
sox10 Ab1-sox10 AB standard conditions Long-pec spinal cord glioblast (sensu Vertebrata) IHC
Ab1-sox10 Day 4 spinal cord oligodendrocyte IHC
Ab1-sox10 AB + MO3-cdc73 standard conditions Long-pec spinal cord glioblast (sensu Vertebrata) IHC
Ab1-sox10 Day 4 Not Detected spinal cord oligodendrocyte IHC
Ab1-sox10 leo1knu6/knu6 standard conditions Long-pec spinal cord glioblast (sensu Vertebrata) IHC
Ab1-sox10 Day 4 Not Detected spinal cord oligodendrocyte IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-elavl IHC AB standard conditions Long-pec neuron
IHC Day 4 neuron
IHC AB + MO3-cdc73 standard conditions Long-pec neuron
IHC Day 4 neuron
IHC leo1knu6/knu6 standard conditions Long-pec neuron
IHC Day 4 neuron
zn-8 IHC AB standard conditions Long-pec motor neuron
IHC AB + MO3-cdc73 standard conditions Long-pec motor neuron
IHC leo1knu6/knu6 standard conditions Long-pec motor neuron
Phenotype Details
Fish Conditions Stage Phenotype
AB + MO3-cdc73 standard conditions Day 4 oligodendrocyte differentiation disrupted, abnormal
Day 4 spinal cord oligodendrocyte decreased amount, abnormal
leo1knu6/knu6 standard conditions Day 4 oligodendrocyte differentiation disrupted, abnormal
Day 4 spinal cord oligodendrocyte decreased amount, abnormal
leo1knu6/knu6; vu12Tg standard conditions Day 4 heart morphology, abnormal
Day 4 heart development disrupted, abnormal
Day 4 oligodendrocyte differentiation disrupted, abnormal
Day 4 pericardium edematous, abnormal
Day 4 pigment cell decreased amount, abnormal
Day 4 pigment cell development disrupted, abnormal
Day 4 spinal cord oligodendrocyte decreased amount, abnormal
Full text @ J. Neurosci.