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ZFIN ID: ZDB-FIG-120627-32
Porreca et al., 2012 - Zebrafish bcl2l is a survival factor in thyroid development. Developmental Biology   366(2):142-152 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Knockdown Reagents:
Anatomical Term:
Stage: Prim-25

Fig. 8 Activation of an apoptotic program in the thyroid primordium of bcl2l, pax2a or nk2.1a morphant embryos. Thyroid and apoptotic cells are stained with hhex riboprobe and active-caspase-3 antibody. Lateral (A) and (B) and ventral views (C) and (D) with anterior to the left, and cross sections (E) and (F) with anterior to the top, of 40 hpf embryos. Experimental morpholino is indicated bottom right, stage bottom left and markers on the left. (A) and (B) Embryos injected with control MO (A) or with bcl2l MO (B). (C) and (D) Embryos injected with control MO (C) or pax2a MO (D) deprived of yolk and flattened on their ventral side. (C′), (D′) Magnification of thyroid primordium in (C) and (D). (E) and (F) Embryos injected with control MO (E) or nk21a MO (F). Arrow indicates active-caspase-3 positive cells in the thyroid primordium.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
hhex WT control Prim-25 thyroid primordium ISH
WT + MO1-bcl2l1 standard conditions Prim-25 thyroid primordium ISH
WT + MO1-nkx2.4b standard conditions Prim-25 thyroid primordium ISH
WT + MO3-pax2a standard conditions Prim-25 thyroid primordium ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 366(2), Porreca, I., De Felice, E., Fagman, H., Di Lauro, R., and Sordino, P., Zebrafish bcl2l is a survival factor in thyroid development, 142-152, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.