ZFIN Figure: Pei et al., 2011, Fig. 3

ZFIN ID: ZDB-FIG-120618-7

ZFIN ID: ZDB-FIG-120618-7

Pei et al., 2011 - A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta. Nucleic acids research 39(8):3156-3165 Full text @ Nucleic Acids Res.

ADDITIONAL FIGURES

EXPRESSION / LABELING:

Genes:	apex1 creb1a polb
Antibody:	Ab1-apex1
Fish:	WT WT + MO1-polb WT + MO4-apex1
Knockdown Reagents:	MO1-polb MO4-apex1
Anatomical Term:	whole organism
Stage Range:	14-19 somites to Protruding-mouth

PHENOTYPE:

Fish:	WT + MO4-apex1
Knockdown Reagent:	MO4-apex1
Observed In:	positive regulation of gene expression
Stage:	Prim-5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details

Gene	Antibody	Fish	Conditions	Stage	Qualifier	Anatomy	Assay
apex1	Ab1-apex1	WT	control	14-19 somites		whole organism	WB
	Ab1-apex1			Prim-5		whole organism	WB
	Ab1-apex1			Prim-15		whole organism	WB
	Ab1-apex1			Long-pec		whole organism	WB
	Ab1-apex1			Protruding-mouth		whole organism	WB
	Ab1-apex1	WT + MO1-polb	standard conditions	Prim-5		whole organism	WB
	Ab1-apex1	WT + MO4-apex1	standard conditions	14-19 somites		whole organism	WB
	Ab1-apex1			Prim-5		whole organism	WB
	Ab1-apex1			Prim-15		whole organism	WB
	Ab1-apex1			Long-pec		whole organism	WB
	Ab1-apex1			Protruding-mouth		whole organism	WB
creb1a		WT	control	Prim-5		whole organism	RTPCR
				Prim-5		whole organism	WB
		WT + MO4-apex1	standard conditions	Prim-5		whole organism	WB
				Prim-5		whole organism	RTPCR
polb		WT	control	Prim-5		whole organism	WB
				Prim-5		whole organism	RTPCR
				Protruding-mouth		whole organism	WB
		WT + MO4-apex1	standard conditions	Prim-5		whole organism	WB
				Prim-5		whole organism	RTPCR
				Protruding-mouth	Not Detected	whole organism	WB

Antibody Labeling Details No data available

Phenotype Details

Fish	Conditions	Stage	Phenotype
WT + MO4-apex1	standard conditions	Prim-5	positive regulation of gene expression disrupted, abnormal

Full text @ Nucleic Acids Res.