header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-120216-60
Langenbacher et al., 2012 - Sodium pump activity in the yolk syncytial layer regulates zebrafish heart tube morphogenesis. Developmental Biology   362(2):263-270 Full text @ Dev. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: 20-25 somites
PHENOTYPE:
Fish:
Observed In:
Stage: 20-25 somites

Fig. S1

Reduction of Fibronectin protein deposition around atp1a1la1 mutant myocardium. (A,B) Transverse vibratome sections of 20S stage wild type and atp1a1la1 Tg(myl7:EGFP) embryos. Wild type embryos (A) have Fibronectin protein (green) surrounding the cardiomyocytes of the cardiac cone (blue), while atp1a1la1 mutants (B) have reduced Fibronectin protein deposition.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
fn1a atp1a1a.1la1/la1; twu34Tg standard conditions 20-25 somites heart primordium IHC
twu34Tg standard conditions 20-25 somites heart primordium IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
atp1a1a.1la1/la1; twu34Tg standard conditions 20-25 somites extracellular matrix organization disrupted, abnormal
20-25 somites heart rudiment has fewer parts of type heart rudiment extracellular matrix, abnormal
20-25 somites heart rudiment extracellular matrix composition, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental Biology for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Developmental Biology, 362(2), Langenbacher, A.D., Huang, J., Chen, Y., and Chen, J.N., Sodium pump activity in the yolk syncytial layer regulates zebrafish heart tube morphogenesis, 263-270, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.