header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-FIG-120203-1
Weiner et al., 2012 - Fishing the molecular bases of Treacher Collins syndrome. PLoS One   7(1):e29574 Full text @ PLoS One
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Terms:
Stage Range: 2-cell to Day 5

Fig. 2

Developmental expression pattern of tcof1 by whole mount in situ hybridization.

Lateral (AI, K, L, NQ, S) and dorsal (J, M, R and T) views (anterior regions to the left) of zebrafish embryos hybridized with anti-sense (AD, I, J, L, M, O, P, and R–T) or sense (EH, K, N and Q) zebrafish tcof1 probes. The following stages were analyzed: 2-cell stage (A and E), 6 hpf (B and F), 10 hpf (C and G), 13 hpf (D and H), 24 hpf (IK), 48 hpf (LN), 72 hpf (OR), and 120 hpf (ST). Abbreviations: cs, craniofacial structures; de, diencephalic region; e, eye; g, gut; mb, midbrain; hb, hindbrain; l, lenses; op, olfactory pits; ot, optic tectum; pa, pharyngeal arches; pf, pectoral fin buds. Scale bar: 180 μm for AH; 210 μm for I, J and P; 266 μm for K; 320 μm for L, M and R; 380 μm for N, O, and ST; 530 μm for Q.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
nolc1 WT standard conditions 2-cell whole organism ISH
Shield whole organism ISH
Bud whole organism ISH
10-13 somites diencephalon ISH
10-13 somites immature eye ISH
10-13 somites whole organism ISH
Prim-5 eye ISH
Prim-5 hindbrain ISH
Prim-5 midbrain ISH
Prim-5 pharyngeal arch ISH
Long-pec cranium ISH
Long-pec olfactory pit ISH
Long-pec optic tectum ISH
Long-pec pectoral fin bud ISH
Long-pec pharyngeal arch ISH
Long-pec retina ISH
Protruding-mouth cranium ISH
Protruding-mouth lens ISH
Protruding-mouth optic tectum ISH
Day 5 cranium ISH
Day 5 gut ISH
Day 5 lens ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal PLoS One for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS One