Fig. 5
- ID
- ZDB-FIG-120125-8
- Publication
- Leacock et al., 2012 - A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis
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EWS-FLI1 affects convergence and extension in zebrafish embryos. Heat-shocked control (A) and EWS-FLI1 transgenic (B) embryos at 2 d.p.f. reveals that transgenic embryos are shorter with reduced head development. At the 18 somite stage, in situ hybridization for myoD in heat-shocked control (C) and EWS-FLI1 transgenic (D) reveals a wider somite width (E) and a shorter anterior-posterior axis as measured by the angle between the head and tail (F) in transgenic embryos (*P<0.02, **P<0.001; error bars indicate s.e.m.). |
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Stage: | 14-19 somites |
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Stage Range: | 14-19 somites to Long-pec |