FIGURE

Fig. 2

ID

ZDB-FIG-111025-20

Publication

Madelaine et al., 2011 - Partially redundant proneural function reveals the importance of timing during zebrafish olfactory neurogenesis

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Fig. 2

Zebrafish early-born olfactory neuron development is delayed in the absence of neurog1 function. (A-D) Confocal projections of wild-type (A) or neurog1 mutant (B-D) olfactory placodes at 24 hpf labelled for HuC/D and GFP from the Tg(8.4neurog1:GFP) transgene; mutant embryos show a variable but reduced number (shown as percentage of wild type) of early-born olfactory neurons. (E,F) Confocal projections of wild-type (E) or neurog1 mutant (F) olfactory placodes at 22 hpf labelled for HuC/D; a reduced number of HuC/D-positive neurons is detected in the olfactory placode of mutant embryos at this stage. (G,H) Confocal projections of wild-type (G) or neurog1 mutant (H) olfactory placodes at 19 hpf labelled for HuC/D; a complete absence of HuC/D neurons is apparent in the olfactory anlagen in neurog1 mutant embryos. Dashed white line indicates the boundary of the telencephalon and the olfactory placode; arrowheads indicate HuC/D expression in olfactory placode. Scale bars: 10 μm.

Expression Data

Gene:	GFP
Antibody:	Ab1-elavl
Fish:	sb1Tg neurog1^{hi1059Tg/hi1059Tg}; sb1Tg
Anatomical Terms:	olfactory placode olfactory placode pioneer neuron
Stage Range:	20-25 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	neurog1^{hi1059Tg/hi1059Tg}; sb1Tg
Observed In:	axon extension olfactory placode pioneer neuron olfactory placode development
Stage Range:	20-25 somites to Prim-5

Phenotype Detail

Acknowledgments

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