|ZFIN ID: ZDB-FIG-110929-31|
|Stage Range:||Prim-5 to Prim-25|
Hdac-dependent derepression of sox10 expression is not seen in mitfa mutant embryos. A–F) In situ hybridisation with sox10 probe showing similar levels of sox10 expression in premigratory (arrow, C) and migrating (arrowhead, C) neural crest cells of mitfa mutants whether treated with 1 μM Trichostatin A from 24–48 hpf (B,D,F) or in stage-matched 36 hpf DMSO control mitfa mutants (A,C,E). Compare effect in WT embryos shown in Figure 8. Scale bar: 100 μm.
|mitfaw2/w2||chemical treatment: pharmaceutical||Prim-5||neural crest||ISH|
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