FIGURE

Fig. S4

ID

ZDB-FIG-110929-30

Publication

Greenhill et al., 2011 - An iterative genetic and dynamical modelling approach identifies novel features of the gene regulatory network underlying melanocyte development

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Fig. S4

Mitfa-dependent regulation of sox10 transgenes narrows candidate regulatory elements. RNA encoding wild-type mitfa (WT) or the mutant form (w2) was injected into Tg(sox10(7.2):gfp) (7.2) and Tg(sox10(4.9):gfp) (4.9) embryos. Note that at 6 hpf, only the former, but not the latter, show GFP induction. As a control, sibling embryos injected with the same constructs were fixed and examined for induction of sox10; note that embryos injected with the wild-type mitfa showed robust induction of sox10 expression. Scale bar, 500 μm. For quantification, see Table S1.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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