FIGURE

Fig. 1

ID
ZDB-FIG-110622-20
Publication
Cederlund et al., 2011 - mab21l2 transgenics reveal novel expression patterns of mab21l1 and mab21l2, and conserved promoter regulation without sequence conservation
Other Figures
All Figure Page
Back to All Figure Page
Fig. 1

Identification of gene regulatory regions in zebrafish mab21l2. Schematic of the zebrafish mab21l2 gene, and the mab21l2 promoter-reporter constructs and their expression domains (A). Epifluorescent images of wholemount larvae injected with mab21l2:EGFP promoter constructs (B–P). The 2.2-kb construct shows some activity in the forebrain and neural tube (B–D). In contrast, the 4.9- and 7.2-kb constructs direct expression in most known mab21l2expression domains (E–P). At <18–24 somites, they direct EGFP expression in the developing optic tectum, forebrain, and neural tube (E,F,H,I,K,N). At <25 hpf, both promoter constructs drive expression in the lens (inset in J). At <33 hpf, EGFP is still expressed by cells in the optic tectum, branchial arches, neural tube, and in tissue surrounding the heart (G,J,L,O). At <62 hpf, EGFP-positive cells are apparent in the eye (M,P). White arrowheads, tectum; white arrows, neural tube; red arrowheads, eye; red arrows, heart; yellow arrowheads, forebrain; yellow arrows, branchial arches. F,I,K,N, dorsal views; B–D,E,G,H,J,L,M,O,P, lateral views.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Dev. Dyn.