FIGURE

Fig. 6

ID

ZDB-FIG-110429-16

Publication

Fujita et al., 2011 - Assembly and patterning of the vascular network of the vertebrate hindbrain

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Abnormal connections between the lateral dorsal aortae and posterior hindbrain channels in cxcr4a morphants. (A-D) Example of a misdirected vessel in cxcr4a MO-injected zebrafish. Confocal images of the hindbrain vasculature in 36 hpf control (A,C) and cxcr4a (B,D) MO-injected Tg(fli1a:EGFP)^y1 animals. Dorsal (A,B) and lateral (C,D) views. Abnormal connections between the LDA and PHBC are occasionally observed in cxcr4a morphants (yellow arrows), but are never found in control MO-injected animals. The confocal image stacks used to generate these images are shown in Movies 5 and 6 in the supplementary material. Scale bar: 50 μm.

Expression Data

Gene:	EGFP
Fish:	y1Tg y1Tg + MO7-cxcr4a
Knockdown Reagent:	MO7-cxcr4a
Anatomical Terms:	lateral dorsal aorta primordial hindbrain channel primordial hindbrain channel angiogenic sprout
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	y1Tg + MO7-cxcr4a
Knockdown Reagent:	MO7-cxcr4a
Observed In:	basilar artery primordial hindbrain channel angiogenic sprout
Stage:	Prim-25

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development