FIGURE

Fig. 6

ID

ZDB-FIG-100804-10

Publication

Roman et al., 2002 - Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels

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Fig. 6

Zebrafish acvrl1 is expressed predominantly in the cranial blood vessels that become dilated in vbg mutants. Whole-mount in situ hybridization using acvrl1 (A-D) or tie1 (E-H) riboprobes on 40 hpf embryos. (A,B) Expression of acvrl1 is strongest in cranial vessels, including the first arch artery (AA1), internal carotid artery (ICA), caudal division of the internal carotid artery (CaDI), basal communicating artery (BCA) and optic vein (OV). Expression in the lateral dorsal aortae (LDA) is moderate. (C,D) Very weak acvrl1 expression is present in the dorsal aorta (DA) and posterior cardinal vein (PCV) (C, low magnification; D, high magnification). In general, tie1 is more widely expressed in cranial endothelium (E,F) than acvrl1, although relative expression in the CaDI is weaker than acvrl1 expression. In the LDA (F), DA and PCV (G, low magnification; H, high magnification), tie1 expression is qualitatively similar to acvrl1. (A,C,D,E,G,H) Lateral view, anterior to the left. (B,F) Dorsal view, anterior to the left. no: notochord.

Expression Data

Genes:	acvrl1 tie1
Fish:	WT
Anatomical Terms:	aortic arch 1 basal communicating artery caudal division of the internal carotid artery dorsal aorta internal carotid artery lateral dorsal aorta optic vein posterior cardinal vein
Stage:	Prim-25

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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