FIGURE

Fig. 5

ID
ZDB-FIG-100616-78
Publication
Znosko et al., 2010 - Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development
Other Figures
(all 10)
All Figure Page
Back to All Figure Page
Fig. 5

Pea3 ETS factors are required for heart development. (A?L) In situ hybridization showing cardiac gene expression at 24hpf (A?H) and 48hpf (I?L). Knock-down of multiple Pea3 ETS factors altered amhc (D; red arrowhead indicates midline of embryo) and vmhc expression (H; cell population and spatial arrangement in yellow bracket). Cardiac looping was severely affected in 3EtsMO-injected embryos as shown by expression of cmlc2 (K, L). (M) Quantification of effects on heart looping in MO-injected embryos as exemplified in I; normal looping, K; no looping, L; reverse looping.

Expression Data
Genes:
Fish:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-5 to Long-pec

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagents:
Observed In: (all 6)
Stage Range: Prim-5 to Long-pec

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 342(1), Znosko, W.A., Yu, S., Thomas, K., Molina, G.A., Li, C., Tsang, W., Dawid, I.B., Moon, A.M., and Tsang, M., Overlapping functions of Pea3 ETS transcription factors in FGF signaling during zebrafish development, 11-25, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.
Your Input Welcome
We welcome your input and comments. Please use this form to recommend updates to the information in ZFIN. We appreciate as much detail as possible and references as appropriate. We will review your comments promptly.