ZFIN ID: ZDB-FIG-100429-40
Parant et al., 2010 - Genetic modeling of Li-Fraumeni syndrome in zebrafish. Disease models & mechanisms   3(1-2):45-56 Full text @ Dis. Model. Mech.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Antibody:
Fish:
Condition:
Knockdown Reagents:
Anatomical Term:
Stage: Long-pec
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Long-pec

Fig. 6 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
tp53 Ab3-tp53 TU + MO2-mdm2 standard conditions Long-pec whole organism WB
Ab3-tp53 TU + MO9-tp53 standard conditions Long-pec Not Detected whole organism WB
Ab3-tp53 TU + MO9-tp53 radiation Long-pec whole organism WB
Ab3-tp53 WT standard conditions Long-pec Not Detected whole organism WB
Ab3-tp53 WT radiation Long-pec whole organism WB
Ab3-tp53 tp53zy7/zy7 + MO2-mdm2(AB) standard conditions Long-pec whole organism WB
Ab3-tp53 tp53zy7/zy7(AB) standard conditions Long-pec Not Detected whole organism WB
Ab3-tp53 tp53zy7/zy7(AB) radiation Long-pec whole organism WB
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TU + MO2-mdm2 standard conditions Prim-5 apoptotic process increased occurrence, abnormal
Prim-5 cell population proliferation decreased occurrence, abnormal
Prim-5 regulation of cell cycle increased occurrence, abnormal
Long-pec whole organism lethal (sensu genetics), abnormal
TU + MO2-mdm2 + MO9-tp53 standard conditions Long-pec whole organism viable, normal
tp53zy7/zy7 + MO2-mdm2(AB) standard conditions Long-pec whole organism viable, normal
Full text @ Dis. Model. Mech.