FIGURE

Fig. S5

ID

ZDB-FIG-100408-18

Publication

Veldman et al., 2010 - Tuba1a gene expression is regulated by KLF6/7 and is necessary for CNS development and regeneration in zebrafish

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Fig. S5

KLF6a and KLF7a are induced in regenerating RGCs following optic nerve injury, but only KLF7a is expressed in differentiating RGCs. (A and B) In situ hybridization showing KLF6a induction in retinal ganglion cells 3 days post-optic nerve crush (B) as compared to uninjured retina (A). (C and D) In situ hybridization showing KLF7a induction in retinal ganglion cells 3 days post-optic nerve crush (D) as compared to uninjured retina (C). (E) KLF6a is not expressed in the retina at 48 h post fertilization (hpf). (F) KLF7a is expressed in the differentiating RGCs at 48 hpf. Arrows denote developing GCL. Outer nuclear layer (OLN), inner nuclear layer (INL), and ganglion cell layer (GCL).

Expression Data

Genes:	klf6a klf7b
Fish:	WT
Condition:	surgical manipulation: cranial nerve II
Anatomical Term:	retinal ganglion cell layer
Stage Range:	Long-pec to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Molecular and cellular neurosciences, 43(4), Veldman, M.B., Bemben, M.A., and Goldman, D., Tuba1a gene expression is regulated by KLF6/7 and is necessary for CNS development and regeneration in zebrafish, 370-383, Copyright (2010) with permission from Elsevier. Full text @ Mol. Cell Neurosci.