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General Information
ZIRC
ZFIN ID: ZDB-FIG-100105-6
van't Padje et al., 2009 - Reduction in fragile X related 1 protein causes cardiomyopathy and muscular dystrophy in zebrafish. The Journal of experimental biology   212(Pt 16):2564-2570 Full text @ J. Exp. Biol.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: Long-pec to Protruding-mouth
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Long-pec

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
fxr1 Ab1-fxr1 WT standard conditions Protruding-mouth atrium IHC
Ab1-fxr1 Protruding-mouth cardiac ventricle IHC
myl7 WT standard conditions Long-pec heart ISH
WT + MO1-fxr1 standard conditions Long-pec heart ISH
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab-MF20 IHC WT control Long-pec atrium cardiac muscle cell
IHC Long-pec cardiac ventricle cardiac muscle cell
IHC WT + MO1-fxr1 standard conditions Long-pec atrium cardiac muscle cell
IHC Long-pec cardiac ventricle cardiac muscle cell
Ab-S46 IHC WT control Long-pec atrium cardiac muscle cell
IHC WT + MO1-fxr1 standard conditions Long-pec atrium cardiac muscle cell
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-fxr1 standard conditions Long-pec atrium tubular, abnormal
Long-pec cardiac ventricle tubular, abnormal
Long-pec heart decreased functionality, abnormal
Long-pec heart linear, abnormal
Long-pec heart looping disrupted, abnormal
WT + MO2-fxr1 standard conditions Long-pec atrium elongated, abnormal
Long-pec atrium separated from sinus venosus, abnormal
Full text @ J. Exp. Biol.