FIGURE

Fig. 5

ID

ZDB-FIG-091121-5

Publication

Pittman et al., 2008 - Pathfinding in a large vertebrate axon tract: isotypic interactions guide retinotectal axons at multiple choice points

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Fig. 5

Axon-axon interactions strongly influence retinotectal pathfinding. (A) Transplants yield GFP-expressing donor RGCs in host eyes. (B-E) Dorsal views, 5 dpf, rostral upwards. Donor axons labeled with brn3c:GFP; pathfinding errors indicated by yellow stars. (B′-E′) Error quantitation. (B,B′) In wild-type> wild-type transplants, donor axons pathfind perfectly. (C,C′) By contrast, when transplanted into ast hosts, wild-type axons make significantly more errors. (D,D′) As expected, ast donor axons make many errors in ast hosts. (E,E′) However, when transplanted into wild-type hosts, ast axons make significantly fewer errors. Scale bar: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

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