Fig. 8
Effects of ectopic cdx1b expression on the development of enteroendocrine cells in the intestine. A-E: Wild type (A), CMV-GFP-injected (B, C), and CMV-cdx1b-injected (D, E) 96-hr post-fertilization (hpf) deyolked embryos hybridized with glucagon antisense RNA probes. F: Comparison of glucagon-expressing enteroendocrine cell numbers between CMV-GFP-injected (n = 29) and CMV-cdx1b-injected (n = 27) embryos. Error bars indicate standard errors. *P < 0.001. Ac, pancreatic α cells; ee, enteroendocrine cells. Scale bars = 100 μm. |