FIGURE

Fig. 3

ID

ZDB-FIG-081201-3

Publication

Esterberg et al., 2008 - Tailbud-derived Bmp4 drives proliferation and inhibits maturation of zebrafish chordamesoderm

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Fig. 3

Sizes of the notochord and chordoneural hinge (CNH) are influenced by Bmp4 activity during late gastrulation. (A-E) shha expression in 14-somite stage embryos. Insets are lateral views of the CNH. (F-J) shha expression in sections through somites 5-10 of 18-somite stage embryos. Insets are cropped images of the same section stained with DAPI. The mean number of DAPI-stained cells from 10 experimental embryos was subjected to one-way ANOVA, followed by a two-tailed, equal variance t-test. (G,H,J) Asterisks indicate significance (P<0.001). (K-O) ntl expression in 24 hpf embryos. CNH domains are indicated with arrowheads, arrows indicate to ectopic tail formation. (A-E) Dorsal views, with anterior towards the left. (K-O) Lateral views, with anterior towards the left.

Expression Data

Genes:	shha tbxta
Fish:	WT WT + MO3-bmp4 w30Tg WT + MO2-fstl1a + MO4-fstl1b
Condition:	heat shock
Knockdown Reagents:	MO2-fstl1a MO3-bmp4 MO4-fstl1b
Anatomical Terms:	chordo neural hinge notochord
Stage Range:	14-19 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO3-bmp4 w30Tg WT + MO2-fstl1a + MO4-fstl1b
Condition:	heat shock
Knockdown Reagents:	MO2-fstl1a MO3-bmp4 MO4-fstl1b
Observed In:	chordo neural hinge notochord notochord cell notochord development
Stage Range:	14-19 somites to Prim-5

Phenotype Detail

Acknowledgments

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