Overexpression of admp or tr-admp RNA and in snailhouse. admp RNA (600 pg) or tr-admp RNA (600 pg) was injected at the one-cell stage into the progeny of snailhouse heterozygous fish. (A–C) Phenotypes were observed live after 1 day of development or (D–I) after in situ hybridization. (D–F) pax 2.1 and myo D in dark blue, hgg1 and krox 20 in red at the five- to seven-somite stage. (G–I) her5 and fkd6 in dark blue, hgg1, krox 20, and ntl in red at the six-somite stage. (A) Uninjected, -/+ or +/+ embryo. (B) Uninjected, snailhouse C4 phenotype. (C) admp-injected snailhouse mutant, C2 phenotype. (B, C) The eye is reduced in (C), compare with (B) (arrowhead). (D, G) Uninjected, -/+ or +/+ embryo. (E) Uninjected, snailhouse C4 phenotype. (F) admp-injected homozygous snailhouse embryo, C2 phenotype. (H) Uninjected, snailhouse C4 phenotype. The neural crest is expanded. (I) tr-admp-injected homozygous snailhouse embryo, C5 phenotype.