FIGURE

Fig. 9

ID

ZDB-FIG-080508-33

Publication

Gray et al., 2001 - Zebrafish deadly seven functions in neurogenesis

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Fig. 9

Analysis of trunk sensory neurons in des^b420 mutants. Dorsal view (anterior to the left) of a 20-h wild-type (A) and mutant (B) embryo showing islet2 expressing RB neurons. Arrowheads denote the absence of RB neurons in the spinal cord of des^b420 mutants. All three des alleles examined had a similar decrease in RB cells (b420 = 2.5 ± 0.2, b638 = 2.6 ± 0.2, and tp37 = 2.3 ± 0.1 compared to wild type = 3.1 ± 0.2). Lateral view of 72-h wild-type (C) and mutant (D) embryo showing Hu-expressing DRG neurons (arrowheads). (E) islet2-expressing RB neurons and Hu-expressing DRG neurons were counted in hemisegments 5–9; n = 10 embryos for RB counts and n = 6 embryos for DRG counts. See Fig. 7 legend for details regarding statistics. Scale bar, 20 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	notch1a^b420/b420 (AB)
Observed In:	dorsal root ganglion neuron Rohon-Beard neuron
Stage Range:	20-25 somites to Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 237(2), Gray, M., Moens, C.B., Amacher, S.L., Eisen, J.S., and Beattie, C.E., Zebrafish deadly seven functions in neurogenesis, 306-323, Copyright (2001) with permission from Elsevier. Full text @ Dev. Biol.