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ZIRC
ZFIN ID: ZDB-FIG-080505-45
Bertrand et al., 2008 - CD41+ cmyb+ precursors colonize the zebrafish pronephros by a novel migration route to initiate adult hematopoiesis. Development (Cambridge, England)   135(10):1853-1862 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage: Protruding-mouth

Fig. S4 Circulation is not required for translocation of hematopoietic precursors to the pronephric tubules or anterior pronephros. (A,B) silent heart morphants did not develop circulation, as shown by erythrocyte pooling (black brackets). (D,E) cmyb:eGFP+ cells translocated normally to the pronephric tubules (majority of ductal cells flanked by white brackets), and migrated to the anterior pronephri (arrowheads). (C,F) cmyb:eGFP+ cells (asterisk) only rarely appeared (3/18 morphants) within the CHT. All animals photographed at 72 hpf with dorsal side upwards, anterior towards the left.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
zf169Tg + MO1-tnnt2a standard conditions Protruding-mouth blood circulation disrupted, abnormal
Protruding-mouth pronephric tubule hematopoietic stem cell position, normal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development