FIGURE

Fig. 5

ID

ZDB-FIG-080502-4

Publication

Kreiling et al., 2008 - Suppression of the endoplasmic reticulum calcium pump during zebrafish gastrulation affects left-right asymmetry of the heart and brain

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

Ca²⁺-sensitive gene expression in the dorsal forerunner cells. (A–F) Syto11 labeling in the dorsal forerunner cells (DFC) at 7 hpf. The dorsal forerunner cells are present in the same location in the DMSO-treated control embryos (A–C), as they are in the thapsigargin-treated embryos (D–F). (G–L) ntl and lrdr RNA in situ hybridizations. DMSO-treated control embryos express ntl in the margin, notochord, and dorsal forerunner cells at 7 hpf (G and H) and express lrdr in the dorsal forerunner cells at 8 hpf (I). Thapsigargin treatment resulted in a strong down-regulation of ntl expression in the dorsal forerunner cells (J and K) and led to a complete inhibition of lrdr expression (L). Scale bar = 50 μm.

Expression Data

Genes:	dnah9 tbxta
Fish:	WT
Condition:	chemical treatment: thapsigargin
Anatomical Terms:	forerunner cell group margin
Stage:	Shield

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Mechanisms of Development, 125(5-6), Kreiling, J.A., Balantac, Z.L., Crawford, A.R., Ren, Y., Toure, J., Zchut, S., Kochilas, L., and Creton, R., Suppression of the endoplasmic reticulum calcium pump during zebrafish gastrulation affects left-right asymmetry of the heart and brain, 396-410, Copyright (2008) with permission from Elsevier. Full text @ Mech. Dev.