FIGURE

Fig. 6

ID

ZDB-FIG-080429-15

Publication

Park et al., 2002 - olig2 is required for zebrafish primary motor neuron and oligodendrocyte development

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

olig2 promotes oligodendrocyte development. (A, B) Transverse sections through trunk spinal cord (sc) of 48-hpf embryos hybridized with sox10 RNA probe. Brackets indicate ventral spinal cord and arrows point to sox10 expression in lateral line. Spinal cord expression of sox10 was absent from embryo injected with olig2 MO, whereas lateral line expression was normal (B). (C-E) Transverse sections of 72-hpf embryos hybridized with dm20/plp RNA probe. Arrows indicate dm20/plp-expressing oligodendrocytes. Embryos injected with olig2 MO did not express dm20/plp (D), whereas those injected with olig2 mRNA had a small but significant increase in the number of dm20/plp-expressing cells (E) (see Table 1). Scale bar, 20 μm.

Expression Data

Genes:	plp1a sox10
Fish:	WT WT + MO1-olig2
Knockdown Reagent:	MO1-olig2
Anatomical Terms:	lateral line spinal cord oligodendrocyte
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-olig2
Knockdown Reagent:	MO1-olig2
Observed In:	oligodendrocyte oligodendrocyte development spinal cord
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 248(2), Park, H.-C., Mehta, A., Richardson, J.S., and Appel, B., olig2 is required for zebrafish primary motor neuron and oligodendrocyte development, 356-368, Copyright (2002) with permission from Elsevier. Full text @ Dev. Biol.