FIGURE

Fig. 1

ID

ZDB-FIG-080323-1

Publication

Londin et al., 2007 - Churchill regulates cell movement and mesoderm specification by repressing Nodal signaling

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Fig. 1

chch inhibition results in axial and somite defects. The effect of inhibiting chch was examined using a morpholino and a dominant-negative construct. Microinjection of chch-ATGMO results in a broad, misshapen notochord (arrow) and misshapen somites and a shortened axis (B). Microinjection of chch-EnR, results in a similar phenotype as the morpholino, a broad, misshapen notochord, and enlarged and misshapen somites formed (C). chch mRNA overexpression produces embryos that are wild-type in appearance (D). Arrowheads point to the notochord. All embryos are 24 hpf.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-churc1
Knockdown Reagent:	MO1-churc1
Observed In:	brain notochord somite whole organism
Stage:	Prim-5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.