FIGURE

Fig. 8

ID
ZDB-FIG-070925-50
Publication
Cha et al., 2005 - Cyclooxygenase-1 signaling is required for vascular tube formation during development
Other Figures
All Figure Page
Back to All Figure Page
Fig. 8

COX-1 knockdown results in gastrulation defect at high dose. Injection of 10 ng cox1-MO results in gastrulation arrest at ~50% epiboly stage (A). Gastrulation arrest defect by cox1-MO can be rescued by co-injecting synthetic cox1 RNA, mutated in MO-binding site (B). Black bar indicates the percentage of embryos that survived to tailbud (C). In the rescue experiments (lane 3, 4), we tested at least 80 embryos from two independent experiments, while in cox1 RNA injection groups (lane 5, 6), at least 50 embryos from two independent experiments were analyzed.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 282(1), Cha, Y.I., Kim, S.H., Solnica-Krezel, L., and Dubois, R.N., Cyclooxygenase-1 signaling is required for vascular tube formation during development, 274-283, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.