FIGURE

Fig. 1

ID

ZDB-FIG-050725-1

Publication

Cha et al., 2005 - Cyclooxygenase-1 signaling is required for vascular tube formation during development

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Fig. 1

cox1 transcripts localize to posterior mesoderm organs. Whole mount in situ hybridization of cox1 (A–H) reveals that its transcripts are ubiquitously present at shield stage (A) and localize posterior half of the embryos at tailbud stage (B–C) from side view (B) and from posterior view (C). cox1 co-localizes with pax2 (H) and fli1 (G) at 7 somite stage, indicating its expression in posterior intermediate mesoderm and posterior lateral mesoderm. During late somitogenesis stage, cox1 transcripts strongly stain posterior mesoderm (D). At 24 hpf, cox1 can be seen in various mesodermal structures (E). Expression of cox1 is not altered in casanova mutant, deficient in endoderm derivatives (F). Arrow indicates the distal end of pronephric duct, letter v indicates the vasculature and arrowhead points to the distal hypochord. Scale bar: 100 μm.

Expression Data

Genes:	fli1 pax2a ptgs1
Fish:	WT sox32^unspecified
Anatomical Terms:	blood vasculature hypochord intermediate mesoderm lateral plate mesoderm mesoderm notochord pronephric duct whole organism
Stage Range:	Shield to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 282(1), Cha, Y.I., Kim, S.H., Solnica-Krezel, L., and Dubois, R.N., Cyclooxygenase-1 signaling is required for vascular tube formation during development, 274-283, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.