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ZIRC
ZFIN ID: ZDB-FIG-070813-6
Hirata et al., 2007 - Zebrafish relatively relaxed mutants have a ryanodine receptor defect, show slow swimming and provide a model of multi-minicore disease. Development (Cambridge, England)   134(15):2771-2781 Full text @ Development
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage: Long-pec

Fig. 1 ryr mutant embryos exhibit slow swimming and weak muscle contractions in response to touch. (A-E) Mechanosensory stimulation induced a wild-type embryo (48 hpf) to swim away rapidly. (F-O) Touch induced an ryr mutant embryo (48 hpf) to swim, but only slowly. (P) Superimposition of all the frames from a video showing normal displacement of the trunk and tail during a swimming episode induced by tactile stimulation of a wild-type sibling. (Q) Displacement of the trunk and tail during swimming in ryr mutants is smaller compared with that of wild-type siblings. For P and Q, the heads of embryos were pinned on a Sylgard dish leaving most of the trunk and tail free.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ryr1bmi340/mi340 standard conditions Long-pec fast-twitch skeletal muscle fiber contraction decreased occurrence, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development