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ZFIN ID: ZDB-FIG-070813-6
Hirata et al., 2007 - Zebrafish relatively relaxed mutants have a ryanodine receptor defect, show slow swimming and provide a model of multi-minicore disease. Development (Cambridge, England)   134(15):2771-2781 Full text @ Development
Observed In:
Stage: Long-pec

Fig. 1 ryr mutant embryos exhibit slow swimming and weak muscle contractions in response to touch. (A-E) Mechanosensory stimulation induced a wild-type embryo (48 hpf) to swim away rapidly. (F-O) Touch induced an ryr mutant embryo (48 hpf) to swim, but only slowly. (P) Superimposition of all the frames from a video showing normal displacement of the trunk and tail during a swimming episode induced by tactile stimulation of a wild-type sibling. (Q) Displacement of the trunk and tail during swimming in ryr mutants is smaller compared with that of wild-type siblings. For P and Q, the heads of embryos were pinned on a Sylgard dish leaving most of the trunk and tail free.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
ryr1bmi340/mi340 standard conditions Long-pec fast-twitch skeletal muscle fiber contraction decreased occurrence, abnormal
ZFIN wishes to thank the journal Development (Cambridge, England) for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Development