Fate map of the posterodorsal and anteroventral pancreatic buds. A: Polar plot of the locations of the posterodorsal and anteroventral pancreatic bud progenitors at 6 hours postfertilization (hpf). These points are the pancreas positive locations seen in Figure 2A. B-D: Confocal slices of representative 40 hpf embryos. B: Example of embryo with labeled cells in the anteroventral bud (purple circles in A). C: Embryo with rhodamine dextran-labeled cells in the posterodorsal bud (yellow squares in A). D: Embryo with labeled cells in both buds (blue triangles in A). Arrows point to labeled cells that colocalize with the structure of interest. Asterisks (*) point to rhodamine dextran-labeled cells that are not in the pancreas or liver. The dashed line encircles the location of the ventral bud, and the solid line encircles the location of the dorsal bud.
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