FIGURE

Fig. 8

ID

ZDB-FIG-070219-34

Publication

Nair et al., 2007 - Requirements for Endothelin type-A receptors and Endothelin-1 signaling in the facial ectoderm for the patterning of skeletogenic neural crest cells in zebrafish

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Fig. 8

Edn1-deficient ectoderm recapitulates the suc/edn1^-/-mutant phenotype. Whole-mount RNA in situ hybridizations (A,B) with immunohistochemistry for biotin-dextran (C,D). (A-C) Dorsolateral views. hand2 expression at 30 hpf (A) is lost in suc;edn1^-/- mutants (B). (C) Wild-type embryos that receive ectoderm from suc;edn1^-/- donors lose hand2 expression adjacent to the transplanted ectoderm (brown cells, arrow). (D) Transverse cryosection through the arches of the embryo in panel C show that donor cells are confined to ectoderm (arrow, brown cells).

Expression Data

Gene:	hand2
Fish:	WT edn1^{tf216b/tf216b}
Anatomical Term:	pharyngeal arch
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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